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- *************************
- * Histone H2A signature *
- *************************
-
- Histone H2A is one of the four histones, along with H2B, H3 and H4, which
- forms the eukaryotic nucleosome core. Using alignments of histone H2A
- sequences [1,2] we selected, as a signature pattern, a conserved region in the
- N-terminal part of H2A. This region is conserved both in classical S-phase
- regulated H2A's and in variant histone H2A's which are synthesized throughout
- the cell cycle.
-
- -Consensus pattern: A-G-L-x-F-P-V
- -Sequences known to belong to this class detected by the pattern: ALL.
- -Other sequence(s) detected in SWISS-PROT: NONE.
- -Last update: June 1994 / Text revised.
-
- [ 1] Wells D.E., Brown D.
- Nucleic Acids Res. 19:2173-2188(1991).
- [ 2] Thatcher T.H., Gorovsky M.A.
- Nucleic Acids Res. 22:174-179(1994).
-